Topic: Genome Analysis / Gene Regulation
Supervisor: Wyeth W. Wasserman, University of British Columbia
Website: www.cmmt.ubc.ca/wasserman and www.cisreg.ca
PROJECT: Immediate openings are available for post-doctoral scientists interested in the application of computational approaches to the analysis and interpretation of regulatory sequences governing human gene transcription. Depending on background and interest, the post-doctoral scientist may work on the analysis of patient genome sequences to identify genetic variation within regulatory sequences, design new algorithms for the prediction of transcription factor binding sites, implement advanced databases for regulatory sequence annotation, or work closely with laboratory partners to design regulatory sequences for potential use in gene therapy procedures. As a group, we are particularly proud of the success of the past post-doctoral trainees who have obtained interesting jobs in academia and industry.
Sample papers related to the research:
-Portales-Casamar E, et al (2010) A regulatory toolbox of MiniPromoters to drive selective expression in the brain. Proc Natl Acad Sci U S A. 107(38):16589-94.
-Malhotra D, et al (2010) Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis. Nucleic Acids Res. 38(17):5718-34.
-Portales-Casamar E, et al (2010) JASPAR 2010: the greatly expanded open-access database of transcription factor binding profiles. Nucleic Acids Res. 38(Database issue):D105-10.
-Andersen MC, et al (2008) In silico detection of sequence variations modifying transcriptional regulation. PLoS Comput Biol. 4(1):e5.
QUALIFICATIONS: The successful candidate will hold a PhD recently awarded (within 24 months) for research in the life sciences or a quantitative field of science or mathematics. We are open to applicants from diverse fields interested in a transition to a career in computational biology, but computationally gifted researchers with a demonstrated interest in the biomedical or life sciences will have an advantage. Demonstrated experience in computer programming is required, preferably using java, perl or python. Experience in the use of SQL-based databases is preferred.
DETAILS: Two positions are available immediately. Each grant-funded position is for an initial one-year appointment (by UBC guidelines), with funding available for at least a further one-year extension based on performance. Salary is commensurate with experience, and is based on funding guidelines from the Canadian Institutes for Health Research. More information about UBC policies is available (http://www.hr.ubc.ca/faculty_relations/recruitmentguide/postdocs.html).
LOCATION: Research is conducted at the Centre for Molecular Medicine and Therapeutics, located at the Child and Family Research Institute on the campus of BC Children’s Hospital, in the middle of beautiful Vancouver. There is highly convenient transit and cycling access.
APPLYING: Please email a CV, a statement of interest and the names and contact information for three references to: Ms. Dora Pak (dora[ at ]cmmt.ubc.ca). Applications will be accepted until the positions are filled.
UBC hires on the basis of merit and is committed to employment equity. We encourage all qualified applicants to apply. However, Canadians and permanent residents of Canada will be given priority. Due to the number of resumes we receive, we are unable to confirm receipt of submissions over the phone, or provide the status of competitions except to those who are selected for an interview.
Please mention ScholarshipNet when applying for this position
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